Six Cancer Diagnoses Affecting His Fertility, a 45 Year Old Father Now Cherishes the Three Children He Thought He’d Lose the Chance to Have

“Some people say I’m the most unlucky person there is,” Jenkins told WNDU News.

“I think I’m probably the luckiest person there is because I’m still alive,” he added, noting that there was a time he feared cancer would prevent him from ever becoming a father.

Testicular cancer, which begins in the cells that produce sperm, is highly treatable — even in advanced stages — according to the National Cancer Institute. Kidney cancer, which affects tens of thousands of Americans each year, can be harder to detect early; symptoms may include blood in the urine, fatigue, weight loss, persistent fever, or pain on one side of the lower back.

The National Cancer Institute says that renal cell carcinoma (kidney cancer) is considered the most common type of all kidney cancer, accounting for 80% of other kidney cancers.

Of all his diagnoses, Jenkins has faced Hodgkin lymphoma the most, enduring multiple relapses over the years as he continues to fight with resilience and purpose

WATCH: Understanding the Types of Lymphoma

Lymphoma treatment largely depends on the nature of your specific diagnosis. For non-Hodgkin lymphoma patients, their cancer is more likely to spread randomly and be discovered in different groups of lymph nodes in the body. Hodgkin lymphoma cancers, on the other hand, are more likely to grow consistently from one group of lymph nodes directly to another.

WATCH: The type of lymphoma you have matters.

They are both cancers of the lymphatic system, which includes lymph nodes, spleen, bone marrow, and other immune tissues. Their symptoms can overlap, including swollen lymph nodes, fatigue, fever, night sweats, and unexplained weight loss. However, the way they are treated may vary.

According to Jenkins’ GoFundMe, he’s been fighting cancer since 1999. While undergoing treatment over the decades, his body has endured collateral damage. He says he’s experienced congestive heart failure (when the heart doesn’t pump enough blood), chronic kidney disease, sarcoidosis (inflammation of organs), and neuropathy, a known side effect of chemotherapy.

Treating Neuropathy Symptoms

“Neuropathy is probably one of the most challenging side effects,” says  Dr. Renata Urban, a gynecologic oncologist at the University of Washington in Seattle.

Neuropathy results from damage to the peripheral nerves.

It usually resolves after chemotherapy treatment, but sometimes symptoms can persist. While it’s typically characterized by numbness or a pins-and-needles sensation in the hands and feet, neuropathy can have several different symptoms, including:

• Weakness in the hands or feet
• Stabbing or burning pain in the hands or feet
• Difficulty gripping, such as when holding a fork
• Difficulty with fine motor skills, such as writing or buttoning a shirt

Doctors have several strategies for helping patients deal with this side effect. Once a patient begins experiencing the symptoms of neuropathy, they’ll be carefully monitored to make sure it doesn’t get worse. Before each chemotherapy infusion, the attending oncologist will assess whether the symptoms have progressed. If the symptoms worsen, they may adjust the dose or delay treatment. They may also try switching to another chemotherapy drug.

“I have congestive heart failure because of one of the chemo drugs they had back in the ’90s,” Jenkins explained.

“They removed one kidney, I have one kidney, unfortunately, that kidney isn’t working so great. I have an autoimmune disease, and I’ve had a fungal infection that went systemic.”

“Since I was 21, I knew that wasn’t always going to be a possibility because of all the treatments, but there’s the miracle of modern science, and so I’m blessed,” Jenkins said.

Jenkins received chemotherapy every three weeks and puts his body on the line all for his children and his wife, Miranda.

“He’s incredible, all of the things he’s been through… he’s an incredible person,” Miranda Jenkins said.

Cancer’s Impact on Fertility

“Since I was 21, I knew that wasn’t always going to be a possibility [of having children naturally] because of all the [cancer] treatments, but there’s the miracle of modern science, and so I’m blessed,” Jenkins said, explaining his worries about the effect cancer treatment would have on his fertility.

Fertility struggles are a genuine concern among cancer patients, as certain cancer treatments can cause infertility. Fortunately, in many cases, efforts can be made before beginning treatment to help preserve fertility.

Even without a diagnosis, many couples, at one point or another, experience infertility. The Centers for Disease Control and Prevention (CDC) says within the U.S., “about one in five” married women between the ages of 15 and 49 with no prior births are unable to get pregnant after trying for a year. Additionally, “one in four” of women in this group struggle to get pregnant or carry the pregnancy to term.

WATCH: How does chemotherapy affect fertility?

Infertility can be a side effect of cancer treatment due to how it impacts the body. Various cancer treatments, including chemotherapy and radiation, can affect both men’s and women’s fertility. Before undergoing cancer treatment, patients should speak to their doctors about fertility preservation if they wish to have a family in the future.

Patients should also recognize that infertility is a problem that affects so many people hoping to be parents, and nothing to be ashamed of.

The American Psychological Association said in its Monitor on Psychology Magazine, “A diagnosis of infertility — the inability to get pregnant after a year or more of trying — can lead to depression, anxiety, and other psychological problems, trigger feelings of shame and failure to live up to traditional gender expectations, and strain relationships.”

Among men, infertility can “cut into a man’s feelings of masculinity” and “can lead to issues of shame and embarrassment,” psychologist William D. Petok told the outlet.

Cancer’s Impact on Male Fertility

Cancer treatments like chemotherapy can damage sperm in men, and hormone therapy can decrease sperm production, according to the National Cancer Institute. Radiation treatment can also lead to lower sperm count and testosterone levels, impacting fertility.

WATCH: Dr. Terri Woodard explains fertility preservation options patients have when going through cancer treatment.

Possible side effects of cancer treatment should be discussed with your doctor before starting treatment. Men may have the option to store their sperm in a sperm bank before treatment to preserve their fertility.

RELATED: Don’t Be Ashamed – The VA Has Treatment To Help Deal With Incontinence After Prostate Cancer Surgery

This sperm can then be used later as part of in vitro fertilization (IVF).

Understanding Christopher’s Many Cancer Journeys

In the early stages, kidney cancer may not cause noticeable symptoms. However, what a patient experiences can differ widely depending on the tumor’s type, size, and location. Below are some potential symptoms and side effects that individuals with kidney cancer might encounter:

• Blood in the urine
• Lower back pain on one side
• Tiredness and fatigue
• Weight loss
• Reduced appetite
• Lumps or growths on the lower back or the side
• High temperature and fever that doesn’t seem to go away
• Anemia: low counts of red blood cells

Surgery is often the primary approach for treating kidney tumors, with the goal of fully removing the cancer. However, this option is typically considered when the tumor is still localized—meaning it’s a manageable size and hasn’t spread (metastasized) to other parts of the body. There are several types of surgical procedures used to treat kidney cancer, including:

• Radical nephrectomy
• Partial nephrectomy
• Cytoreductive nephrectomy
• Laparoscopic and robotic surgery
• Mastectomy

Treatment Options for Kidney Cancer: What You Should Know

Kidney cancer can be treated through a range of approaches—each designed to target cancer cells in different ways. Your care team will help determine the best path forward based on your diagnosis, overall health, and personal preferences. Here’s a breakdown of key treatment options:

• Radiofrequency Ablation (RFA): This minimally invasive procedure uses a needle inserted directly into the tumor. Electric currents and radiofrequency waves heat and destroy the cancerous tissue from within.
• Cryoablation: In this technique, extremely cold probes are placed into the tumor to freeze and kill cancer cells. It’s often used for small tumors or patients who aren’t candidates for surgery.
• Chemotherapy: Chemotherapy uses powerful medications to stop cancer cells from growing, dividing, or surviving. While kidney cancer is often resistant to traditional chemotherapy, certain drugs may be used in specific cases or in combination with other therapies.
• Radiation Therapy: High-energy particles or waves are used to damage and destroy cancer cells. The two main types are:
  • External Beam Radiation: Delivered from outside the body, targeting the tumor with precision.
  • Internal Radiation (Brachytherapy): Places radioactive material directly inside or near the tumor.
• Immunotherapy: This innovative approach activates your immune system to better detect and attack cancer cells. Treatments like immune checkpoint inhibitors help the body overcome cancer’s defenses and mount a stronger response.
• Targeted Therapy: These drugs zero in on specific genes or proteins that fuel cancer growth. One notable example is belzutifan (Welireg), approved by the FDA in August 2021 for patients with Von Hippel-Lindau (VHL) disease-related kidney cancers. Belzutifan blocks a protein called HIF-2α, which normally supplies oxygen and nutrients to cancer cells—cutting off this pathway can shrink tumors significantly.
• Combination Therapy: In many cases, doctors may recommend a blend of treatments—such as immunotherapy paired with targeted therapy—to increase effectiveness and tailor care to your unique needs.

WATCH: Immunotherapy Needs to be Tailored

The Immunotherapy Offering Kidney Cancer Patients Hope

The immunotherapy drug Keytruda is approved to treat some types of kidney cancer. Immunotherapy is a powerful cancer treatment option that uses the patient’s own immune cells to fight the cancer after a bit of reengineering in a lab. The drug’s approval stemmed from the KEYNOTE-564 trial.

“The goal (of the study) was to see if (the drug) can prevent kidney cancer coming back,” Dr. Toni Choueiri, director of the Lank Center for Genitourinary Oncology at the Dana-Farber Cancer Institute and lead author of the study, tells SurvivorNet. (The study itself was supported by pharmaceutical company Merck & Co. and conceived by Dr. Choueiri and some co-authors.)

Keytruda was approved for the adjuvant treatment (additional cancer treatment given after the primary treatment) of patients with renal cell carcinoma at an intermediate-high or high risk of recurrence following nephrectomy, or following nephrectomy and resection (removal) of metastatic lesions.

Understanding Testicular Cancer

A testicular cancer diagnosis is rare, but it is the most common form of cancer diagnosed in young men.

Depending on the stage, the disease is considered highly treatable. Treatment options can include chemotherapy and radiation, but often, the first line of treatment is surgery to remove the testicle, which contains the cancerous cells.

Symptoms of testicular cancer can be subtle. Some people may even confuse the early symptoms, such as a small mass in their testicle, as an injury. But when these signs are dismissed, the cancer can grow and become worse.

Dr. Edwin Posadas, the medical director of the Urologic Oncology Program at Cedars-Sinai Cancer, previously told SurvivorNet that some men may even notice blood in their ejaculate as a result of testicular cancer. “This symptom is less common but always bad,” he said.

“It’s not uncommon to see men come in with masses on their scrotum and have inflammation of the scrotal wall; they develop pain as a result. A lump is the most common symptom of testicular cancer,” Dr. Posadas adds.

Men should regularly conduct self-exams of their testicles for anything unusual.

Testicular Cancer symptoms can include:

• Breast growth or soreness
• Early puberty in boys
• Low back pain (a potential symptom of advanced testicular cancer)
• Shortness of breath, chest pain, or a cough (a possible symptom of advanced testicular cancer)
• Belly pain (a possible symptom of advanced testicular cancer)
• Headaches or confusion (a possible symptom of advanced testicular cancer)

Understanding the Types of Lymphomas

Hodgkin Lymphoma and non-Hodgkin lymphoma are the two main types of lymphoma, and their classification depends on the type of white blood cells and the presence (or absence) of Reed-Sternberg cells.

They are both cancers of the lymphatic system, which includes lymph nodes, spleen, bone marrow, and other immune tissues. Their symptoms can overlap, including swollen lymph nodes, fatigue, fever, night sweats, and unexplained weight loss. However, the way they are treated may vary.

WATCH: Dr. Jason Westin explains symptoms associated with lymphoma

If doctors are unable to detect the Reed-Sternberg cell (a giant cell derived from B lymphocytes), then the lymphoma is categorized as Non-Hodgkin lymphoma. However, if Reed-Sternberg cells are present, the lymphoma is diagnosed as Hodgkin Lymphoma.

WATCH: The type of lymphoma you have matters.

Lymphoma treatment largely depends on the nature of your specific diagnosis. For non-Hodgkin lymphoma patients, their cancer is more likely to spread randomly and be discovered in different groups of lymph nodes in the body. Hodgkin lymphoma cancers, on the other hand, are more likely to grow consistently from one group of lymph nodes directly to another.

B-Cell vs. T-Cell Lymphoma

Doctors classify non-Hodgkin lymphoma based on the type of lymphocytes affected:

B-cell lymphomas account for nearly 85% of non-Hodgkin lymphoma cases. These cancers originate in cells responsible for producing antibodies that identify and fight infections.
T-cell lymphomas, making up 15% of cases, arise in T-cells, which directly attack harmful invaders like bacteria and viruses.
Identifying whether the lymphoma is B-cell or T-cell helps guide treatment options tailored to the disease’s behavior and progression.

Types of B-Cell Lymphoma

• Diffuse large B-cell lymphoma
• Follicular lymphoma
• Small lymphocytic lymphoma (SLL) / Chronic lymphocytic leukemia (CLL)
• Mantle cell lymphoma
• Marginal zone lymphomas
• Burkitt lymphoma

Types of T-Cell Lymphoma

• T-lymphoblastic lymphoma/leukemia
• Peripheral T-cell lymphomas
• Cutaneous T-cell lymphoma
• Aggressive vs. Indolent (slow-growing) Lymphomas

One of the key distinctions doctors make when diagnosing non-Hodgkin lymphoma is how rapidly the cancer grows and spreads.

Indolent (slow-growing) lymphomas tend to develop over time and may not require immediate aggressive treatment.
Aggressive lymphomas spread quickly and need intensive treatment to prevent further progression.

Dr. Jennifer Crombie, medical oncologist at Dana-Farber Cancer Institute, explains that understanding whether the lymphoma is indolent or aggressive is essential, as they require very different treatment approaches.

What Treatment for Non-Hodgkin Lymphoma Looks Like?

Lymphoma treatment largely depends on the nature of your specific diagnosis. For non-Hodgkin lymphoma patients, their cancer is more likely to spread randomly and be discovered in different groups of lymph nodes in the body. Hodgkin lymphoma cancers, on the other hand, are more likely to grow consistently from one group of lymph nodes directly to another.

WATCH: Non-Hodgkin lymphoma treatment options

“There are some lymphomas that are very treatable but not curable,” Dr. Lawrence Piro told SurvivorNet.

Dr. Lawrence Piro is the President and CEO of The Angeles Clinic and Research Institute in Los Angeles, a Cedars-Sinai affiliate. He adds that some lymphomas progress quickly if left untreated.

Non-Hodgkin lymphoma treatment depends on the type, stage, and how fast it grows. People with aggressive non-Hodgkin lymphoma can expect to get a chemotherapy combination called R-CHOP, which is a drug cocktail consisting of chemotherapy drugs plus an antibody drug and a steroid to treat diffuse large B-cell non-Hodgkin lymphoma.

R-CHOP stands for:

• R: Rituximab (Rituxan) is a monoclonal antibody that attaches to a specific protein called CD20, which sits on the surface of B cells. It targets cancerous cells and destroys them.
• C: Cyclophosphamide is a type of chemotherapy drug
• D: Doxorubicin hydrochloride (hydroxydaunomycin) is a type of chemotherapy drug
• V: Vincristine sulfate (Oncovin) is a type of chemotherapy drug
• P: Prednisone is a steroid that lowers inflammation

Patients receiving R-CHOP receive the drug in six cycles that are three weeks apart.

“R-CHOP is a cocktail of drugs. There are five different drugs in that recipe,” Dr. Jennifer Crombie, medical oncologist at Dana-Farber Cancer Institute, tells SurvivorNet.

WATCH: Understanding R-CHOP treatment.

R-CHOP side effects can include:

• Tiredness and weakness
• Hair loss
• Mouth sores
• Bruising and bleeding
• Increased risk of infection
• Appetite loss and weight loss
• Changes in bowel movements

Immunotherapy and targeted therapy are also treatment options for non-Hodgkin lymphoma patients.

Rituximab (Rituxan) was the first immunotherapy drug approved to treat some forms of non-Hodgkin lymphoma. “Rituximab is the immunotherapy that has been approved the longest, and we have the most experience with lymphoma,” Dr. Chong tells SurvivorNet.

Rituxan has side effects, including fever, chills, swelling under the skin, itching, and mild shortness of breath.

Brentuximab vedotin (Adcetris) is a relatively new targeted treatment for non-Hodgkin lymphoma and Hodgkin lymphoma. This drug is an antibody-drug conjugate that combines an antibody (a type of protein that recognizes foreign substances in the body) with a drug that treats cancer. It uses a particular protein to deliver medicine directly to the cancer cell.

Non-Hodgkin lymphoma can also be treated with radiation, which aims beams of intense energy at the cancer to stop cancer cells from growing and dividing.

Questions for Your Doctor

If you are dealing with a lymphoma diagnosis, it’s important to ask your doctor a series of questions so you will have an idea of what your next steps will look like. To help you during this difficult time, SurvivorNet has some questions to kickstart your conversation with your physician.

• What type of lymphoma do I have?
• What does my pathology report say about my diagnosis?
• Should I get a second opinion before I explore possible treatment options?
• Based on my diagnosis, what do you anticipate my treatment path?
• What common side effects should I expect when I begin treatment?
• Will I be able to continue working and performing normal daily activities during treatment?
• Where can I get help working with the insurance company regarding treatment costs?
• Who do you recommend I get mental health help from during my treatment?

Learn more about SurvivorNet's rigorous medical review process.

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